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Mechanisms include reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression supporting neuronal survival, angiogenesis improving cerebral blood flow, and modulation of dopamine and serotonin systems

In cell studies, luteolin i nhibits TNF-alpha and IL-6 released via suppressing NF-B .[ref] TNF-alpha and IL-6 are linked to many chronic diseases caused by elevated inflammatory cytokines