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Although not the focus of phase I/II trials, patients treated with ADI-PEG20 did not show any reduction in the melanoma progression and whether the treatment may prolong survival seems to depend on the disease stages during treatment [140, 141]

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Enrichment of transiently transfected mesangial cells by cell sorting after cotransfection with GFP

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However, for those without a deficiency, such high doses are unnecessary and should be avoided without a doctor's recommendation