Progranulin (mouse) ELISA Kit Pack Size:2 x 96 wells Y-27632 dihydrochloride is an orally

Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor (ROCK-I Ki=220 nM

Plasma levels are reduced in obese humans and low levels are associated with insulin-resistance

Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg

mature ubiquitin polypeptide (amino acids 1-76)

SB202190 induces autophagy

Progranulin (mouse) ELISA Kit Pack Size:2 x 96 wells Y-27632 dihydrochloride is an orallyProgranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting