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N., Botha, T., Ojo, B

GrimmTChovanovaZMuchovaJSumegovaKLiptakovaADurackovaZet alInhibition of NF-kappaB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol)

Based on the working hypothesis of P-gp-dependent collateral sensitivity [14,15,16,17], we examined the ability of tamoxifen as a collateral sensitivity drug for two reasons: a) tamoxifen has been previously shown to activate P-gp ATPase at clinically achievable concentration (46 M) [20, 21], and b) tamoxifen is widely used in the treatment of estrogen receptor-positive breast cancer [22]

Spine 25 , 29402952 (2000)