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Evidence from several animal studies demonstrates the safe and effective use of antioxidants such as N-acetylcysteine (NAC), a thiol compound and precursor of glutathione (GSH), to overcome CWA-induced oxidative stress and associated acute lung injuries

The formula also includes milk thistle extract, which helps increase cysteine levels in the liver, enhancing glutathione production

UCK2 inhibitors are still in preclinical development, but are positioned in combination with 5FU or other cytotoxics that alter nucleotide pools

Itaconate inhibits ferroptosis of macrophage via nrf2 pathways against sepsis-induced acute lung injury

All authors OB12 Group read and approved the final manuscript