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Mutation in this gene has been associated with Amish infantile epilepsy syndrome
The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired
The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6
They form a three-tiered signaling module composed of MAPKKKs
MB10369-100
IKKα Polyclonal Antibody-BS79555 Cells in 3D Hydrogels Mutation in this gene hasIKK Polyclonal Antibody Sizes: 50l, 100l Catalogue Numbers: BS79555 50, BS79555 100 Product: 1mg ml in PBS with 0. 02% sodium azide, 50% glycerol, pH7. 2 Swiss Prot: O15111 Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB All Applications: WB,1: 500 1: 2000 Background: This gene encodes a member of the serine threonine protein kinase family. The encoded protein, a component of a cytokine activated protein complex that is an inhibitor of the
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