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In addition, a large amount of mtDNA is released during the formation of NETs, which acts on HCC cells to activate the cGAS-ncNF-B signaling pathway and induce the invasion of HCC cells [177]

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Graphical abstract Similar content being viewed by others 1 Introduction The GLOBOCAN 2022 (Global Cancer Observatory) report (2024), prepared by the International Agency for Research on Cancer, threw up numbers and projections that estimate an ever-rising cancer incidence in the global population

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