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Experimental design and sample collection Following a 2-week acclimatization period, male C57BL/6 mice were randomly assigned to either a control group (CON, n = 8) fed standard chow or an obesity modeling group (n = 16) receiving a high-fat diet (HFD

Image reconstructions were conducted using Hiscan Reconstruct software (Hiscan Medical Technology Co., Ltd., China), while quantitative morphological analysis was accomplished using Hiscan Analyzer software (Hiscan Medical Technology Co., Ltd., China)

This process of collagen synthesis by fibroblasts may be critical to contribute to the overall restoration and healing of damaged tissues

model 2 paths (Fig

Future research should adhere to the highest standards of preclinical and translational study design, including rigorous blinding, randomization, and power analysis, to enhance the validity and reproducibility of the results