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Honce, J

Under stressful conditions, spermatozoa undergo an intrinsic apoptotic pathway characterized by the generation of mitochondrial ROS, the loss of mitochondrial membrane potential, caspase activation, phosphatidylserine exposure, and oxidative DNA damage [15]

Subsequently, the authors determined general radiosensitivity ( D 0 dose reducing surviving fraction to 37%), quasi-threshold doses ( D q ), and extrapolation numbers ( n ) from the survival curves and correlated these parameters with the cellular levels of GPx, catalase, CuZn superoxide dismutase (Cu/Zn-SOD), and Mn superoxide dismutase (Mn-SOD)

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Lee E, Burgess DJ