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For example, when upregulated expression of drug-resistance genes (e.g., Mdr1/Abcb1) in the intestinal flora is detected, the risk of antibiotic use can be flagged in advance to prevent exacerbation of bacterial resistance

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Among those with chronic fatigue, interventions with a demonstrated benefit in ME/CFS may prove useful, most prominently lifestyle management (pacing, optimization of energy management, regular rests, etc.) or even pharmacologic interventions such as naltrexone [11,308]

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A medical consultation is required prior to starting any protocol