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Applying 30 to 60 minutes before sleep is ideal

Improves Mood and Reduces Symptoms of Depression The generation of neurotransmitters like dopamine and serotonin, which are vital for mood control, depends on vitamin B12

it also bolsters immune function, enhancing our body's ability to ward off pathogens and maintain optimal health

J Endocrinol 217(3):291301 Barlow KM et al (2019) Melatonin as a treatment after traumatic brain injury: a systematic review and meta-analysis of the pre-clinical and clinical literature

Key context: Epitalon (Tetrapeptide studied for telomerase activation and telomere elongation in human somatic cells)