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FIGURE 3 On the other hand, at increased levels, UA is considered as a marker of oxidative stress (Strazzullo and Puig, 2007) due to accumulation of reactive oxygen species (Jossa et al., 1994

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Because it inhibits the proliferation of Treg cells, leptin, a pro-inflammatory adipocytokine, is unusually increased in SLE patients and speeds up the course of lupus nephritis (232, 233)

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