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Folate-targeted nanoparticles for glutamine metabolism inhibition enhance anti-tumor immunity and suppress tumor growth in ovarian cancer

Lippman, S

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The balance between two subsets of macrophages is known: the M1-like macrophages, which are associated with antimicrobial and pro-inflammatory activity, and the M2-like macrophages, which are mostly involved in tissue repair and are associated with an immune-modulatory activity