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Mdm2 inhibitor nutlin-3a induces p53-dependent apoptosis via transcription-dependent and independent pathways and overcomes fludarabine-resistance in CLL

PLB treatment significantly decreased iron ions and LPO, suggesting its role in ferroptosis inhibition, but YTHDF1 overexpression reversed these effects (Fig

Future studies examining 5-Amino-1MQ before and after will likely incorporate advanced genetic profiling and comprehensive metabolomic analysis to predict individual responses with greater accuracy

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