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Confocal and immunostaining analysis showed increased expression of matrix metalloproteinase 1 (MMP-1) in unconstrained explants compared to constrained (Table 1)

Chlorin-e6 also called meso-tetraphenyl morphine Mn (III) chloride, which is a generation- three photosensitizer, showed effective internalization within malignant melanoma cells after being encapsulated in liquid crystalline nano dispersions (LCNs), and they showed notable photodynamic effects after being exposed to radiation as compared to free photosensitizer (PS) [269]

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