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For example, the mesolimbic dopaminergic pathway composed of dopaminergic (DA) neurons in the ventral tegmental area (VTA) and their projections to the nucleus accumbent (NAc) is crucial for the recognition of emotionally salient stimuli such as reward and aversion

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This could suggest that the antitumor effect is related to the up-regulation of cleaved caspase-3, poly (ADP-ribose) polymerase (PARP) and Bax, and down regulation of Bcl-2 [56]

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