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Originally developed by Metabolic Pharmaceuticals (Australia) in the early 2000s, it has been investigated extensively in metabolic and lipolysis research as a fragment that retains hGHs fat-mobilising activity without its insulin-like or growth-promoting effects

Additionally, in animal models, riboflavin deficiency was also found to induce down-regulated expression of key osteogenic markers in the femur, including Runx2, Osterix, and BMP-2/Smad1/5/9 cascade [12]