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However, it remains unclear whether these acute changes translate into long-term impacts on endothelial health, as a substantial portion of the existing data originated from preclinical studies 13-15

Model validation and performance assessment We also used previously developed validation methods [2123] to select the best-performing model among a number of different plausible models

For World No Tobacco Day 2018, WHO has joined with the World Heart Federation to highlight the link between tobacco and cardiovascular diseases (CVD) - the worlds leading causes of death, responsible for 44% of all NCD deaths, or 17.9 million deaths annually

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