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Medications Used for Nausea and Vomiting During Pregnancy Drug FDA category Recommendations for pregnancy Recommendations for breastfeeding Dolasetron Domperidone Granisetron Metoclopramide Ondansetron Prochlorperazine Promethazine Pyridoxine B C B B B C C A No human data: probably compatible Limited human data: probably compatible No human data: probably compatible Limited human data: potential toxicity No human data: probably compatible No human data: potential toxicity No human data: probably compatible Compatible Trimethobenzamide C No human studies Safety unknown No human studies No teratogenicity

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Dopaminergic activity increases in ways that enhance motivation, focus, and reward processing without the dysregulation associated with stimulant drugs