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h-i , Immunoblots for NMHC-IIA, NMHC-IIB, Nectin-1, and Actin in lysates from parental HEK293T or SK-N-SH cells or pools of cells treated for 48 h with gRNAs/Cas9 complexes targeting MYH9, MYH10 and NECTIN1 as indicated (n = 3)

Numerous studies have identified abnormal alterations in various cytokines in the CSF and peripheral blood of SZ patients (see Table 3 ), most of which are pro-inflammatory cytokines (IL-1, IL-2, IL-8, TNF-, and IFN-) (188191), with a smaller proportion being anti-inflammatory cytokines (including TGF-1, IL-4, and IL-10) (192)

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- Gentle and non-irritating