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The Journal of Child Psychology and Psychiatry

SS-31 (elamipretide) , a mitochondria-targeted peptide that stabilizes cardiolipin to support energy production, became the first FDA-approved mitochondrial therapeutic in 2025, though only for the rare Barth syndrome, with the brain rationale still mechanistic and no cognitive trials

The clinical use of furosemide and ethacrynic acid

In addition, hyperglycemia generates the spontaneous interaction of glucose with protein without any enzymes, which indicates the non-enzymatic glycation or glycosylation process

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