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The representative SASP factors include pro-inflammatory cytokines, chemokines, and proteases, which can cause an imbalance in cartilage hemostasis, resulting in degradation or other dysfunctions (Li and Pei, 2012)

Injury Prevention: Strengthened connective tissues like tendons and ligaments protect the skeletal muscle from excessive strain

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Lanifibranor also significantly reduced ALT (26.1 U/L), AST (15.1 U/L), hsCRP (2.0 mg/L), HOMA-IR (5.8 units), HbA1c (0.4% points), and triglycerides (43.4 mg/dL)