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In addition, autophagy could also be promoted by palmatine through activation of the AMPK/mTOR signaling pathway that may contribute to its antioxidant and neuroprotective activity ( in vitro (Song et al., 2021)

Weeks 2 to 4: Significant functional improvements reported

Nutrients 8(12):E798 Funding This study was supported by a grant of University of Perugia (Fondo di finanziamento della ricerca di base del Dipartimento di Scienze Chirurgiche e Biomediche, year 2015) and registered in ISRCTN number 14115156

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Navarro J, Rainisio M, Harms HK, Hodson ME, Koch C, Mastella G, et al