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Conversely, research on 9-me-BC is currently limited to studies using injections of the drug either systemically or directly into the brain
Additionally, patients with specific medical conditionssuch as kidney disease, liver disease, or particular blood disorderswill require careful monitoring and possibly dosage adjustments by our clinical team, as excessive vitamin B12 supplementation could lead to complications
There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision
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