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The extraordinary ligand binding properties of human serum albumin

The formation and biological significance of N7-guanine adducts

Given that both diet composition and adiposity can each substantially impact the gut microflora in obese mice 24 , we conducted a secondary endpoint study using animals given the same series of diets to test the hypothesis that NNMTi treatment combined with LD, but not LD alone, shifts the cecal microbiome profile of obese animals to be similar to age-matched LD controls that were never given a high-fat diet

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Robust, head-to-head studies are needed to clarify the therapeutic potential and mechanistic diversity of these compounds before their clinical application in DOR management can be meaningfully assessed