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L-Glutathione: L-Glutathione is a powerful antioxidant that plays a crucial role in detoxifying the liver
(2) upregulating hENT1 expression (2.7-fold increase) and enhancing gemcitabine transmembrane transport (Konat et al., 2024)
Dysregulated iron metabolism, including increased expression of transferrin receptors and ferritin degradation, leads to iron accumulation, contributing to ferroptosis ( 2+ acts as a cofactor for LOXs and prolyl hydroxylase, which are critical enzymes involved in lipid peroxidation and oxygen homeostasis ( During the first trimester, hepcidin levels increase, while in the second trimester, hepcidin levels decrease despite stable serum iron levels
Nanomedicine 12 , 835844 (2016)