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Considering that the two-pronged EDT/SDT mediated by ZFPG + US could effectively activate anti-tumor immunity, we utilized Luc-RM-1 cells to establish lung colonization models to evaluate whether these interventions could inhibit the metastasis of prostate cancer to the lung, the experimental procedure followed the illustration depicted in Fig

Schincaglia GP, Hebert E, Farina R, Simonelli A, Trombelli L

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Conversely, chronic disease states such as hypertension or hyperglycemia generate reactive oxygen species that further exacerbate mitochondrial damage, creating a self-perpetuating cycle

For example, in HUEVCs cells, Sirt4 regulates ATP homeostasis via AMPK and mitochondrial inner membrane ADP/ATP-translocase 2, which inhibited malonyl-CoA decarboxylase, and led to an increase in malonyl-CoA levels [99]