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The [Ca 2+ ] i increases observed in cultured neurons under these conditions may result from a direct excitatory action by binding ionotropic receptors and/or from an indirect effect involving the stimulation of endogenous glutamate synaptic release

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"Anti-Inflammatory Activity of Black Soldier Fly Oil Associated with Modulation of TLR Signaling: A Metabolomic Approach." International Journal of Molecular Sciences 2023, 24(13), 10634