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According to estimates, the Caucasian populations lifetime chance of having a CSCC ranges from 7 to 11% (9% to 14% for men and 4% to 9% for women) [56]
Head Face Pain 74 YuS.-Y.CaoX.-T.ZhaoG.YangX.-S.QiaoX.-Y.FangY.-N.et al (2011)
Importantly, this increase in DNA damage was linked to an activation of the ataxia telangiectasiamutated (ATM) signaling pathway [103], corroborating previous work that showed that mutant ATXN3 expression resulted in p53 activation and apoptotic cell death [105]