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Primary study: A study in Iran among 45 obese people with MASLD found that alpha-lipoic acid (600 mg twice daily before meals) combined with vitamin E (400 IU) for 12 weeks did not improve body composition, most markers of liver injury, or hepatic steatosis compared to vitamin E with placebo

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Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, Kalyanaraman B, Mutlu GM, Budinger GR, Chandel NS (2010) Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

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