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Resulting operational taxonomic units (OTUs) were assigned a taxonomic lineage using the Ribosomal Database Project (RDP) classifier (v2.5) with a custom Greengenes (v13_5) training set 28,29,30,31

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It encompasses the structural and functional aspects of the cellular surroundings, but also the presence of metabolites such as glucose, amino acids and lipids within the TME, as well as environmental factors such as hypoxia and acidity (81)

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The issue of migration has therefore become even more critical for a significant number of people groups