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however, tachyphylaxis may develop if H2 blockade is used daily for more than 4 weeks

ARA-290 targets peripheral nerve repair and inflammation through the innate repair receptor, while Dihexa works centrally on synaptic architecture

This is particularly important for peptides accessed multiple times

Keeping a close eye on how the patient is doing is key to adjusting the treatment as needed

A method for preventing radiation-induced ototoxicity in an individual in need thereof comprising intratympanic administration of a pharmaceutical composition comprising a therapeutic agent selected from a JNK inhibitor, TRPV modulator, an MET channel inhibitor, and an otoprotectant to the individual in need thereof, wherein the pharmaceutical composition is administered prior to onset of radiation therapy, and wherein the composition provides sustained release of the therapeutic agent into the ear for a period of at least 5 days after a single administration