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2021;64:102555 Elsevier

Anti-angiogenic drugs (VEGF pathway inhibitors and TKI) Mechanisms and clinical manifestations The premise of this type of targeted drugs is that tumor growth is highly dependent on local pathological angiogenesis induced by vascular endothelial growth factor (VEGF), which promotes tumor development by regulating vascular permeability, endothelial cell migration, proliferation, and survival (44)

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The case against my own recommendation A guide is only as honest as its willingness to argue against itself

Its extreme potency means tiny doses suffice, which partially offsets the higher per-milligram cost